5 Bromo DMT

5 Bromo DMT: An Overview

5 Bromo DMT, also known as 5-bromo-N,N-dimethyltryptamine, is a synthetic psychedelic compound that belongs to the tryptamine family. It is a derivative of the naturally occurring psychedelic substance DMT (N,N-dimethyltryptamine). Due to its structural modification—specifically the addition of a bromine atom at the 5-position—it exhibits unique pharmacological properties and effects compared to DMT.

Chemical Structure and Properties

– Chemical Formula: C₁₁H₁₂BrN₂
– Molecular Weight: Approximately 254.1 g/mol
– Appearance: Typically a crystalline powder, often white or off-white
– Stability: Relatively stable under proper storage conditions

The bromine atom at the 5-position on the indole ring significantly alters its affinity for serotonin receptors, which are primarily responsible for its psychoactive effects.

Pharmacology and Effects

While research on 5-Bromo-DMT is limited, it is known to act primarily as a serotonergic psychedelic. Users report experiences that may include:
– Vivid visual hallucinations
– Altered perception of time and space
– Introspective and mystical experiences
– Potential for intense emotional shifts

The onset of effects is generally rapid when vaporized or smoked, lasting around 15 to 30 minutes, similar to other DMT derivatives.

Legality and Safety

The legal status of 5-Bromo-DMT varies by country, often categorized under controlled substances due to its structural similarity to other psychedelics. Because research is limited and its potency can be unpredictable, caution is advised. There are potential risks associated with its use, including psychological distress and unknown long-term effects.

Research and Potential Uses : 5 Bromo DMT

Currently, scientific research into 5-Bromo-DMT is sparse. However, it has garnered interest within the psychedelic community for its unique effects and potential as a tool for consciousness exploration. In the future, it may contribute to understanding serotonergic systems or be explored for therapeutic purposes under controlled conditions.

Conclusion
5-Bromo-DMT is a fascinating synthetic tryptamine that exemplifies how minor chemical modifications can produce new psychoactive substances with distinct effects. As with all psychedelics, responsible use and further research are crucial to fully understanding its properties and safety profile. 5 Bromo DMT. 5 Bromo DMT. 5 Bromo DMT. 5 Bromo DMT.

5-Bromo-DMT (5-bromo-N,N-dimethyltryptamine) is a psychedelic brominated indole alkaloid found in the sponges Smenospongia aurea and Smenospongia echina, as well as in Verongula rigida (0.00142% dry weight) alongside 5,6-dibromo-DMT (0.35% dry weight) and seven other alkaloids.^[1][2][3][4] It is the 5-bromo derivative of DMT, a psychedelic found in many plants and animals.

5-Bromo-DMT is an agonist of the serotonin 5-HT_2A receptor, with an EC₅₀Tooltip half-maximal effective concentration of 3,090 nM.^[5]

Animal studies on 5-Bromo-DMT showed that it produces effects suggestive of sedative and antidepressant activity and caused significant reduction of locomotor activity in the rodent FST model.^[6] In contrast to 5-fluoro-DMT and 5-chloro-DMT, 5-bromo-DMT failed to produce the head-twitch response, a behavioral proxy of psychedelic effects, in rodents.^[7]

5-Bromo-DMT was reported to be psychoactive in humans at doses of 20 to 50 mg via vaporization with mild psychedelic-like effects.^[8]